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Designing for time-to-event endpoints

These vignettes provide an introduction to designing group sequential trials with time-to-event endpoints using gsDesign.

Overview of survival endpoint design
Integer sample size and event counts
Basic time-to-event group sequential design using gsSurv
A Cure Model Calendar-Based Design

Other

Other vignettes.

A gentle introduction to group sequential design
gsDesign package overview
Spending function overview
Conditional Power and Conditional Error
Two-sample normal sample size
Multiplicity graphs
Graphical testing for group sequential design
Vaccine Efficacy Trial Design
Binomial SPRT