Articles

Design fundamentals

Sample size calculation for negative binomial outcomes

Non-inferiority and super-superiority designs

Simulation and validation

Simulating recurrent events

Seasonal event simulation

Verification of sample size calculation via simulation

Score vs Wald tests and sample-size recommendations

Group sequential monitoring

Group sequential design and simulation

Group sequential simulation with completers analysis

Sample size re-estimation

Sample size re-estimation example

SSR simulation study

Diagnosing Blinded Information Calculation Issues

Advanced workflows

Multiple imputation for longitudinal negative binomial counts

AI-assisted gsDesignNB workflows

Published sample-size examples with the gsDesignNB AI skill